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We focus on delivering fast and reliable results using innovative scientific solutions in compliance with FDA 21 CFR Part 210/211, Part 58, and Part 11 regulations. We work hard to ensure we meet our clients’ timelines. We are committed to helping our clients be successful in their pursuit of innovative, life-saving drugs, and we are proud to be a part of your efforts to advance human health. Contact Us We are always happy to discuss your analytical requirements for developing and manufacturing mRNA therapeutics. Our experts can support your rapid journey to market and regulatory approval. Visionary Analytical Solutions, Expertly Executed At Avance, we Visionary Analytical Solutions, Expertly Executed At Avance, we are experts at designing, developing, and validating bioanalytical assays for mRNA therapeutics development and manufacturing. That means faster and more reliable results and innovative solutions to your analytical challenges. We’ve worked at the leading edge of mRNA-based therapeutics for a long time and have developed an extensive portfolio of GLP- and GMP-compliant assay services that surpass regulatory requirements. We specialize in designing, developing, and validating assays f We specialize in designing, developing, and validating assays for biologics development and manufacturing. We focus on delivering fast and reliable results using innovative scientific solutions in compliance with FDA 21 CFR Part 210/211, Part 58, and Part 11 regulations. We work hard to ensure we meet our clients’ timelines. We are committed to helping our clients be successful in their pursuit of innovative, life-saving drugs, and we are proud to be a part of your efforts to advance human health. We are always happy to discuss your analytical requirements for developing and manufacturing mRNA therapeutics. Our experts can support your rapid journey to market and regulatory approval. Science-driven, Regulation-compliant, and Customer-centric Orga Science-driven, Regulation-compliant, and Customer-centric Organization Customized Assay Design: We understand that each cellular or g Customized Assay Design: We understand that each cellular or gene therapy product is unique. Our team works closely with you to design customized potency assays tailored to your specific needs, ensuring accurate evaluation of your product's efficacy. Method Optimization: Our scientists have extensive experience in optimizing potency assay methods. We carefully assess variables, including critical parameters, sample matrices, and analytical techniques, to develop robust and reproducible assays. Reliable Bioanalytical Techniques: We employ a range of cutting-edge techniques, including flow cytometry, qPCR, ELISA, and functional assays, to measure potency accurately. Our advanced instrumentation and rigorous quality control processes guarantee reliable and precise results. Regulatory Compliance: We are well-versed in regulatory guidelines, such as those provided by the FDA, EMA, and ICH. Our potency assays are designed to meet these requirements, ensuring the generation of data suitable for regulatory submissions. Data Analysis and Reporting: Our team provides comprehensive data analysis and interpretation, delivering clear and concise reports. We ensure that you receive actionable insights and recommendations to support your decision-making process. Our Potency Assay Development Service Our Potency Assay Development Service Avance Biosciences is a world-leading CRO that provides CGMP an Avance Biosciences is a world-leading CRO that provides CGMP and GLP-compliant biological testing solutions that support the biological drug development pipeline from discovery through manufacturing. Layer 24 Supporting Your Biopharmaceutical Supporting Your Biopharmaceutical Drug Development Pipeline www.designsoul.com www.avancebio.com sales@avancebio.com 9770 West Little York Road Houston TX 77040, USA 9770 West Little York Road Houston TX 77040, USA 1.877.909.5210 1.877.909.5210 Contact Us Contact Us www.avancebio.com www.avancebio.com About Avance Biosciences Avance Biosciences is a leading contra About Avance Biosciences Avance Biosciences is a leading contract research organization (CRO) specializing in molecular biology, genomics, and cell-based assays. We provide a comprehensive range of services to support drug development, from assay development and validation to clinical sample analysis. With our scientific expertise and cutting-edge technologies, we are committed to delivering accurate, reliable, and timely results to our clients. Contact Us We are always available to discuss your analytical Contact Us We are always available to discuss your analytical needs for potency assay development. Our experts can help support your rapid journey to market and regulatory approval. cell/viral bank copy Confidentiality & Data Security text At Avance Biosciences, we prioritize the confidentiality and security of your data. We follow strict protocols to ensure the protection of your intellectual property and sensitive information. cell/viral bank copy Timely Delivery text We recognize the importance of timely results in the fast-paced drug development industry. We work efficiently to deliver high-quality data within agreed-upon timelines. cell/viral bank copy Customized Approach text We understand that each project is unique, and we tailor our services to meet your specific requirements. Our collaborative approach ensures that your goals and expectations are met. cell/viral bank copy State-of-the-Art Facilities text Avance Biosciences is equipped with advanced instrumentation and facilities necessary for developing and executing complex potency assays. We adhere to strict quality control measures to deliver reliable and accurate results. cell/viral bank copy Scientific Expertise text Our team consists of highly skilled scientists with vast experience in assay development and the biologics field. We stay up-to-date with the latest advancements to provide cutting-edge solutions for our clients. Why Choose Avance Biosciences? Why Choose Avance Biosciences? cell/viral bank copy USP Testing text We provide a wide range of USP testing for lot release, including appearance (USP 631 and USP 790), bioburden (USP 61), and more. cell/viral bank copy Data Analysis and Reporting text Our team provides comprehensive data analysis and interpretation, delivering clear and concise reports. We ensure that you receive actionable insights and recommendations to support your decision-making process. cell/viral bank copy Regulatory Compliance text We are well-versed in regulatory guidelines, such as those provided by the FDA, EMA, and ICH. Our assays are designed and qualified and/or validated to meet these requirements, ensuring the generation of data suitable for regulatory submissions. cell/viral bank copy Reliable Bioanalytical Techniques text We employ a range of cutting-edge techniques, including flow cytometry, qPCR, ELISA, ddPCR, and NGS, to measure potency accurately. Our advanced instrumentation and rigorous quality control processes guarantee reliable and precise results. cell/viral bank copy Method Optimization text Our scientists have extensive experience in optimizing complex assays. We carefully assess variables, including critical parameters, sample matrices, and analytical techniques, to develop robust and reproducible assays. cusotmized assays Customized Assay Design text We understand that each therapeutic product is unique. Our team works closely with you to design customized potency assays tailored to your specific needs, ensuring an accurate evaluation of your product's efficacy. Avance Potency Assay Development Service Avance Potency Assay Development Service www.designsoul.com www.avancebio.com sales@avancebio.com 9770 West Little York Road Houston TX 77040, USA 9770 West Little York Road Houston TX 77040, USA 1.877.909.5210 1.877.909.5210 www.avancebio.com www.avancebio.com Contact Us Contact Us Sample testing under GMP Sample testing under GMP Assay qualification or validation under GMP Assay qualification or validation under GMP Client potency assay technology transfer Client potency assay technology transfer Custom potency assay development Custom potency assay development • Stability Testing • Residuals Testing • Integrity & Purity • Stability Testing • Residuals Testing • Integrity & Purity • Ratio Testing • Identity, Sequence, Quantification • Cell- • Ratio Testing • Identity, Sequence, Quantification • Cell-based Potency Assays • In vitro Transcription (IVT) Science-driven, Regulation-compliant, and Customer-centric Orga Science-driven, Regulation-compliant, and Customer-centric Organization We specialize in designing, developing, and validating assays for biologics development and manufacturing. We focus on delivering fast and reliable results using innovative scientific solutions in compliance with FDA 21 CFR Part 210/211, Part 58, and Part 11 regulations. We work hard to ensure we meet our clients’ timelines. We are committed to helping our clients be successful in their pursuit of innovative, life-saving drugs, and we are proud to be a part of your efforts to advance human health. Contact Us We are always happy to discuss your analytical requirements for developing and manufacturing mRNA therapeutics. Our experts can support your rapid journey to market and regulatory approval. Visionary Analytical Solutions, Expertly Executed At Avance, we Visionary Analytical Solutions, Expertly Executed At Avance, we are experts at designing, developing, and validating bioanalytical assays for mRNA therapeutics development and manufacturing. That means faster and more reliable results and innovative solutions to your analytical challenges. We’ve worked at the leading edge of mRNA-based therapeutics for a long time and have developed an extensive portfolio of GLP- and GMP-compliant assay services that surpass regulatory requirements. We specialize in designing, developing, and validating assays f We specialize in designing, developing, and validating assays for biologics development and manufacturing. We focus on delivering fast and reliable results using innovative scientific solutions in compliance with FDA 21 CFR Part 210/211, Part 58, and Part 11 regulations. We work hard to ensure we meet our clients’ timelines. We are committed to helping our clients be successful in their pursuit of innovative, life-saving drugs, and we are proud to be a part of your efforts to advance human health. We are always happy to discuss your analytical requirements for developing and manufacturing mRNA therapeutics. Our experts can support your rapid journey to market and regulatory approval. Science-driven, Regulation-compliant, and Customer-centric Orga Science-driven, Regulation-compliant, and Customer-centric Organization Potency testing is an essential part of developing cellular and Potency testing is an essential part of developing cellular and gene therapy (CGT) products. The US Food and Drug Administration (FDA) requires sponsors for Investigational New Drug (IND) and Biologics License Applications (BLA) to provide in vitro or in vivo data to demonstrate the potency of the drug product. As such, potency testing plays a critical role in the development and approval of CGT products. At Avance Biosciences, we provide comprehensive services to assist our clients in advancing their therapeutic drug development and meeting FDA requirements efficiently and effectively. We use a case-by-case approach to develop, qualify, or validate custom potency assays in accordance with current Good Manufacturing Practice (cGMP) regulations, ensuring that they comply with the necessary standards for GMP product release. Avance Biosciences is a world-leading CRO that provides CGMP an Avance Biosciences is a world-leading CRO that provides CGMP and GLP-compliant biological testing solutions that support the biological drug development pipeline from discovery through manufacturing. 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We focus on delivering fast and reliable results using innovative scientific solutions in compliance with FDA 21 CFR Part 210/211, Part 58, and Part 11 regulations. We work hard to ensure we meet our clients’ timelines. We are committed to helping our clients be successful in their pursuit of innovative, life-saving drugs, and we are proud to be a part of your efforts to advance human health. Contact Us We are always happy to discuss your analytical requirements for developing and manufacturing mRNA therapeutics. Our experts can support your rapid journey to market and regulatory approval. Visionary Analytical Solutions, Expertly Executed At Avance, we Visionary Analytical Solutions, Expertly Executed At Avance, we are experts at designing, developing, and validating bioanalytical assays for mRNA therapeutics development and manufacturing. That means faster and more reliable results and innovative solutions to your analytical challenges. We’ve worked at the leading edge of mRNA-based therapeutics for a long time and have developed an extensive portfolio of GLP- and GMP-compliant assay services that surpass regulatory requirements. We specialize in designing, developing, and validating assays f We specialize in designing, developing, and validating assays for biologics development and manufacturing. We focus on delivering fast and reliable results using innovative scientific solutions in compliance with FDA 21 CFR Part 210/211, Part 58, and Part 11 regulations. We work hard to ensure we meet our clients’ timelines. We are committed to helping our clients be successful in their pursuit of innovative, life-saving drugs, and we are proud to be a part of your efforts to advance human health. We are always happy to discuss your analytical requirements for developing and manufacturing mRNA therapeutics. Our experts can support your rapid journey to market and regulatory approval. Science-driven, Regulation-compliant, and Customer-centric Orga Science-driven, Regulation-compliant, and Customer-centric Organization Customized Assay Design: We understand that each cellular or g Customized Assay Design: We understand that each cellular or gene therapy product is unique. Our team works closely with you to design customized potency assays tailored to your specific needs, ensuring accurate evaluation of your product's efficacy. Method Optimization: Our scientists have extensive experience in optimizing potency assay methods. We carefully assess variables, including critical parameters, sample matrices, and analytical techniques, to develop robust and reproducible assays. Reliable Bioanalytical Techniques: We employ a range of cutting-edge techniques, including flow cytometry, qPCR, ELISA, and functional assays, to measure potency accurately. Our advanced instrumentation and rigorous quality control processes guarantee reliable and precise results. Regulatory Compliance: We are well-versed in regulatory guidelines, such as those provided by the FDA, EMA, and ICH. Our potency assays are designed to meet these requirements, ensuring the generation of data suitable for regulatory submissions. Data Analysis and Reporting: Our team provides comprehensive data analysis and interpretation, delivering clear and concise reports. We ensure that you receive actionable insights and recommendations to support your decision-making process. Our Potency Assay Development Service Our Potency Assay Development Service Avance Biosciences is a world-leading CRO that provides CGMP an Avance Biosciences is a world-leading CRO that provides CGMP and GLP-compliant biological testing solutions that support the biological drug development pipeline from discovery through manufacturing. Layer 24 Supporting Your Biopharmaceutical Supporting Your Biopharmaceutical Drug Development Pipeline www.designsoul.com www.avancebio.com sales@avancebio.com 9770 West Little York Road Houston TX 77040, USA 9770 West Little York Road Houston TX 77040, USA 1.877.909.5210 1.877.909.5210 Contact Us Contact Us www.avancebio.com www.avancebio.com About Avance Biosciences Avance Biosciences is a leading contra About Avance Biosciences Avance Biosciences is a leading contract research organization (CRO) specializing in molecular biology, genomics, and cell-based assays. We provide a comprehensive range of services to support drug development, from assay development and validation to clinical sample analysis. With our scientific expertise and cutting-edge technologies, we are committed to delivering accurate, reliable, and timely results to our clients. Contact Us We are always available to discuss your analytical Contact Us We are always available to discuss your analytical needs for potency assay development. Our experts can help support your rapid journey to market and regulatory approval. cell/viral bank copy Confidentiality & Data Security text At Avance Biosciences, we prioritize the confidentiality and security of your data. We follow strict protocols to ensure the protection of your intellectual property and sensitive information. cell/viral bank copy Timely Delivery text We recognize the importance of timely results in the fast-paced drug development industry. We work efficiently to deliver high-quality data within agreed-upon timelines. cell/viral bank copy Customized Approach text We understand that each project is unique, and we tailor our services to meet your specific requirements. Our collaborative approach ensures that your goals and expectations are met. cell/viral bank copy State-of-the-Art Facilities text Avance Biosciences is equipped with advanced instrumentation and facilities necessary for developing and executing complex potency assays. We adhere to strict quality control measures to deliver reliable and accurate results. cell/viral bank copy Scientific Expertise text Our team consists of highly skilled scientists with vast experience in assay development and the biologics field. We stay up-to-date with the latest advancements to provide cutting-edge solutions for our clients. Why Choose Avance Biosciences? Why Choose Avance Biosciences? cell/viral bank copy USP Testing text We provide a wide range of USP testing for lot release, including appearance (USP 631 and USP 790), bioburden (USP 61), and more. cell/viral bank copy Data Analysis and Reporting text Our team provides comprehensive data analysis and interpretation, delivering clear and concise reports. We ensure that you receive actionable insights and recommendations to support your decision-making process. cell/viral bank copy Regulatory Compliance text We are well-versed in regulatory guidelines, such as those provided by the FDA, EMA, and ICH. Our assays are designed and qualified and/or validated to meet these requirements, ensuring the generation of data suitable for regulatory submissions. cell/viral bank copy Reliable Bioanalytical Techniques text We employ a range of cutting-edge techniques, including flow cytometry, qPCR, ELISA, ddPCR, and NGS, to measure potency accurately. Our advanced instrumentation and rigorous quality control processes guarantee reliable and precise results. cell/viral bank copy Method Optimization text Our scientists have extensive experience in optimizing complex assays. We carefully assess variables, including critical parameters, sample matrices, and analytical techniques, to develop robust and reproducible assays. cusotmized assays Customized Assay Design text We understand that each therapeutic product is unique. Our team works closely with you to design customized potency assays tailored to your specific needs, ensuring an accurate evaluation of your product's efficacy. Avance Potency Assay Development Service Avance Potency Assay Development Service www.designsoul.com www.avancebio.com sales@avancebio.com 9770 West Little York Road Houston TX 77040, USA 9770 West Little York Road Houston TX 77040, USA 1.877.909.5210 1.877.909.5210 www.avancebio.com www.avancebio.com Contact Us Contact Us Sample testing under GMP Sample testing under GMP Assay qualification or validation under GMP Assay qualification or validation under GMP Client potency assay technology transfer Client potency assay technology transfer Custom potency assay development Custom potency assay development • Stability Testing • Residuals Testing • Integrity & Purity • Stability Testing • Residuals Testing • Integrity & Purity • Ratio Testing • Identity, Sequence, Quantification • Cell- • Ratio Testing • Identity, Sequence, Quantification • Cell-based Potency Assays • In vitro Transcription (IVT) Science-driven, Regulation-compliant, and Customer-centric Orga Science-driven, Regulation-compliant, and Customer-centric Organization We specialize in designing, developing, and validating assays for biologics development and manufacturing. We focus on delivering fast and reliable results using innovative scientific solutions in compliance with FDA 21 CFR Part 210/211, Part 58, and Part 11 regulations. We work hard to ensure we meet our clients’ timelines. We are committed to helping our clients be successful in their pursuit of innovative, life-saving drugs, and we are proud to be a part of your efforts to advance human health. Contact Us We are always happy to discuss your analytical requirements for developing and manufacturing mRNA therapeutics. Our experts can support your rapid journey to market and regulatory approval. Visionary Analytical Solutions, Expertly Executed At Avance, we Visionary Analytical Solutions, Expertly Executed At Avance, we are experts at designing, developing, and validating bioanalytical assays for mRNA therapeutics development and manufacturing. That means faster and more reliable results and innovative solutions to your analytical challenges. We’ve worked at the leading edge of mRNA-based therapeutics for a long time and have developed an extensive portfolio of GLP- and GMP-compliant assay services that surpass regulatory requirements. We specialize in designing, developing, and validating assays f We specialize in designing, developing, and validating assays for biologics development and manufacturing. We focus on delivering fast and reliable results using innovative scientific solutions in compliance with FDA 21 CFR Part 210/211, Part 58, and Part 11 regulations. We work hard to ensure we meet our clients’ timelines. We are committed to helping our clients be successful in their pursuit of innovative, life-saving drugs, and we are proud to be a part of your efforts to advance human health. We are always happy to discuss your analytical requirements for developing and manufacturing mRNA therapeutics. Our experts can support your rapid journey to market and regulatory approval. Science-driven, Regulation-compliant, and Customer-centric Orga Science-driven, Regulation-compliant, and Customer-centric Organization Potency testing is an essential part of developing cellular and Potency testing is an essential part of developing cellular and gene therapy (CGT) products. The US Food and Drug Administration (FDA) requires sponsors for Investigational New Drug (IND) and Biologics License Applications (BLA) to provide in vitro or in vivo data to demonstrate the potency of the drug product. As such, potency testing plays a critical role in the development and approval of CGT products. At Avance Biosciences, we provide comprehensive services to assist our clients in advancing their therapeutic drug development and meeting FDA requirements efficiently and effectively. We use a case-by-case approach to develop, qualify, or validate custom potency assays in accordance with current Good Manufacturing Practice (cGMP) regulations, ensuring that they comply with the necessary standards for GMP product release. Avance Biosciences is a world-leading CRO that provides CGMP an Avance Biosciences is a world-leading CRO that provides CGMP and GLP-compliant biological testing solutions that support the biological drug development pipeline from discovery through manufacturing. 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